DGCR8-dependent efficient pri-miRNA processing of human pri-miR-9-2
نویسندگان
چکیده
منابع مشابه
Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA.
MicroRNAs (miRNAs) are small non-coding RNAs that inhibit expression of specific target genes at the post-transcriptional level. Sequence variations in miRNA genes, including pri-miRNAs, pre-miRNAs and mature miRNAs, could potentially influence the processing and/or target selection of miRNAs. In this study, we have systematically identified single nucleotide polymorphisms (SNPs) associated wit...
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As you will see, all referees acknowledge that the findings are potentially interesting and suitable for publication in EMBO reports. However, both referees 1 and 2 point out that the observed effect of introns on enhancing mature miR163 levels should be extended to other miRNAs. Both referees also mention the inconsistency between your study and the one from Voinnet's lab regarding the require...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2021
ISSN: 0021-9258
DOI: 10.1016/j.jbc.2021.100409